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HOMEZ Antikörper

Der Maus Monoklonal Anti-HOMEZ-Antikörper wurde für FACS und IHC (f) validiert. Er ist geeignet, HOMEZ in Proben von Human zu detektieren.
Produktnummer ABIN7126854

Kurzübersicht für HOMEZ Antikörper (ABIN7126854)

Target

Alle HOMEZ Antikörper anzeigen
HOMEZ (Homeobox and Leucine Zipper Encoding (HOMEZ))

Reaktivität

  • 22
  • 17
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 21
  • 3
Maus

Klonalität

  • 23
  • 1
Monoklonal

Konjugat

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HOMEZ Antikörper ist unkonjugiert

Applikation

  • 23
  • 12
  • 10
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Spezifität

    Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant full-length human HOMEZ protein

    Isotyp

    IgG2a
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human testis, kidney or fetal lung.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    HOMEZ (Homeobox and Leucine Zipper Encoding (HOMEZ))

    Andere Bezeichnung

    HOMEZ

    Hintergrund

    KIAA1443, Homeodomain leucine zipper-containing factor,Homeobox and Leucine Zipper Encoding / HOMEZ
    Cellular localisation: Nucleus.

    Molekulargewicht

    61.24kDa

    Gen-ID

    57594, 632332

    UniProt

    Q8IX15
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