ITLN1/Omentin Antikörper (AA 16-141)

Produktnummer ABIN7126826

Dieses Maus Monoklonal-Antikörper erkennt spezifisch ITLN1/Omentin in IHC (f). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ITLN1/Omentin Antikörper (AA 16-141) (ABIN7126826)

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITLN1/Omentin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Produktdetails anti-ITLN1/Omentin Antikörper

Bindungsspezifität: AA 16-141

Spezifität: Human intelectin-1 (ITLN-1) is a novel identified galactose binding lectin that is usually expressed in the heart, small intestine, and colon. In normal tissues, human intelectin-1 was mainly secreted from gastrointestinal goblet cells along with mucus into the intestinal lumen, and it was also expressed, to a lesser extent, in mesothelial cells and urinary epithelial cells. It is overexpressed in human malignant pleural mesothelioma (MPM). In contrast, sarcomatoid-type MPMs, biphasic MPMs, and poorly differentiated MPMs are rarely positive for intelectin-1, and it is not expressed in other cancers, except in mucus-producing adenocarcinoma.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa16-141) of human Intelectin-1 (ITLN1) protein (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human mesothelioma or colon tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ITLN1/Omentin

Target: ITLN1/Omentin (ITLN1) (Intelectin 1 (Galactofuranose Binding) (ITLN1))

Andere Bezeichnung: ITLN1

Hintergrund: Endothelial lectin HL-1, Galactofuranose binding lectin, hIntL, Intestinal lactoferrin receptor, INTL, ITLN, LFR,Intelectin 1 / Omentin (Epithelioid-Type Malignant Mesothelioma Marker)
Cellular localisation: Cell membrane. Secreted.

Molekulargewicht: 35kDa

Gen-ID: 55600, 50813

UniProt: Q8WWA0