PLP1 Antikörper (AA 272-277)

Produktnummer ABIN7126797

Produktdetails anti-PLP1 Antikörper

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Bindungsspezifität: AA 272-277

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.

Kreuzreaktivität (Details): Human, Mouse, Rat, Tenerife Lizard and Cow.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human brain tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu PLP1

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Andere Bezeichnung: PLP1 (PLP1 Produkte)

Synonyme: GPM6C antikoerper, HLD1 antikoerper, MMPL antikoerper, PLP antikoerper, PLP/DM20 antikoerper, PMD antikoerper, SPG2 antikoerper, Plp antikoerper, PLP1 antikoerper, plp1 antikoerper, DKFZp459O081 antikoerper, DKFZp459O113 antikoerper, DM20 antikoerper, jimpy antikoerper, jp antikoerper, msd antikoerper, rsh antikoerper, plp antikoerper, hld1 antikoerper, mmpl antikoerper, plp1a antikoerper, pmd antikoerper, spg2 antikoerper, DMalpha2c antikoerper, wu:fc27f01 antikoerper, wu:fj36d03 antikoerper, wu:fj42d08 antikoerper, zgc:110499 antikoerper, PLP-B antikoerper, plp1-a antikoerper, plp1-b antikoerper, plp1b antikoerper, proteolipid protein 1 antikoerper, proteolipid protein (myelin) 1 antikoerper, myelin proteolipid protein antikoerper, proteolipid protein 1 L homeolog antikoerper, proteolipid protein 1a antikoerper, proteolipid protein 1 S homeolog antikoerper, PLP1 antikoerper, Plp1 antikoerper, plp1 antikoerper, Tsp_11640 antikoerper, plp antikoerper, plp1.L antikoerper, plp1a antikoerper, plp1.S antikoerper

Hintergrund: Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20,Proteolipid Protein / Myelin PLP
Cellular localisation: Membrane

Molekulargewicht: 23-25kDa

Gen-ID: 5354, 1787

UniProt: P60201