NEUROD2 Antikörper

Produktnummer ABIN7126743

Der Maus Monoklonal Anti-NEUROD2-Antikörper wurde für ELISA, IP, IF, FACS und Coat validiert. Er ist geeignet, NEUROD2 in Proben von Human zu detektieren.

Kurzübersicht für NEUROD2 Antikörper (ABIN7126743)

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NEUROD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Produktdetails anti-NEUROD2 Antikörper

Spezifität: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (i²2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human NEUROD2 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Human brain.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Andere Bezeichnung: NEUROD2

Hintergrund: BHLHa1, class A basic helix loop helix protein 1, NDR2, NDRF, NeuroD-related factor, NeuroD2, neurogenic basic helix loop helix protein, neurogenic differentiation 2, Neurogenic differentiation factor 2, neuronal differentiation 2,NEUROD2 (Neurogenic Differentiation 2) (Transcription Factor)
Cellular localisation: Nucleus.

Molekulargewicht: 41kDa

Gen-ID: 4761, 322431

UniProt: Q15784