FOXB2 Antikörper (AA 1-200)
Kurzübersicht für FOXB2 Antikörper (AA 1-200) (ABIN7126716)
Target
Alle FOXB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-200
-
Spezifität
- The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
-
Kreuzreaktivität (Details)
- Human. Predicted to react in Mouse and Rat.
-
Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
Immunogen
- Recombinant fragment (around aa1-200) of human FOXB2 protein (exact sequence is proprietary)
-
Isotyp
- IgG2a
-
-
-
-
Applikationshinweise
-
Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
Konservierungsmittel
- Azide free
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
Haltbarkeit
- 24 months
-
-
- FOXB2 (Forkhead Box B2 (FOXB2))
-
Andere Bezeichnung
- FOXB2
-
Hintergrund
-
BA159H20.4, Forkhead box B2, Forkhead box protein B2, FOXB 2, Foxb2,FOXB2 (Transcription Factor)
Cellular localisation: Nucleus. -
Molekulargewicht
- 45.58kDa
-
Gen-ID
- 442425, 553843
-
UniProt
- Q5VYV0
Target
-