Lactoferrin Antikörper (AA 614-645)
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- Target Alle Lactoferrin (LTF) Antikörper anzeigen
- Lactoferrin (LTF) (Lactotransferrin (LTF))
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Bindungsspezifität
- AA 614-645
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Lactoferrin Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Ferritin and transferrins manage necessary iron-binding functions for iron metabolism. Transferrins comprise a class of single-chain, two-sited, metal-binding proteins expressed throughout the fluid and cells of vertebrates. The three major types of transferrin include serotransferrin, lactotransferrin (lactoferrin) and ovotransferrin. Lactoferrin is found in milk, tears and leukocytes. It degrades an IgA1protease secreted by Haemophilus influenzae and, consequently, allows the human IgA1antibody to effectively abolish Haemophilus influenzae colonization. Lactoferrin also attenuates the pathogenic potential of Haemophilus influenzae by proteolytic degradation of the Hap adhesin. While lactoferrin may aid in the transmission of human T cell leukemiavirus type 1, it inhibits HIV-1 replication at the level of viral fusion and entry into cells. The inhibitory effects of lactoferrin on mixed lymphocyte reactions suggest that it may have the ability to sense the activation status of lymphocytes.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa614-645) of human Lactotransferrin protein (exact sequence is proprietary)
- Isotyp
- IgG2b
- Top Product
- Discover our top product LTF Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human lactating breast or prostate tissue.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- Lactoferrin (LTF) (Lactotransferrin (LTF))
- Andere Bezeichnung
- LTF (LTF Produkte)
- Synonyme
- LTF antikoerper, GIG12 antikoerper, HLF2 antikoerper, LF antikoerper, Lf antikoerper, Csp82 antikoerper, MMS10R antikoerper, Ms10r antikoerper, PLF antikoerper, TFEW antikoerper, conalbumin antikoerper, lactotransferrin antikoerper, transferrin antikoerper, transferrin (ovotransferrin) antikoerper, LTF antikoerper, CpipJ_CPIJ000114 antikoerper, TF antikoerper, Ltf antikoerper
- Hintergrund
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GIG12, Growth inhibiting protein 12, HLF2, Kaliocin 1, Lactoferrin, Lactoferroxin-C, Lactotransferrin, LF, LTF, Neutrophil lactoferrin, Talalactoferrin,Lactotransferrin / Lactoferrin / LTF
Cellular localisation: Cytoplasm. Secreted. - Molekulargewicht
- 78kDa
- Gen-ID
- 4057, 529517
- Pathways
- Transition Metal Ion Homeostasis
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