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Rekombinanter Annexin a1 Antikörper

ANXA1 Reaktivität: Human WB, IHC (f) Wirt: Maus Monoclonal unconjugated Recombinant Antibody
Produktnummer ABIN7126503
  • Target Alle Annexin a1 (ANXA1) Antikörper anzeigen
    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 129
    • 48
    • 41
    • 11
    • 10
    • 10
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 133
    • 34
    • 8
    • 1
    Maus
    Klonalität
    • 139
    • 36
    Monoklonal
    Konjugat
    • 102
    • 27
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Annexin a1 Antikörper ist unkonjugiert
    Applikation
    • 135
    • 66
    • 63
    • 27
    • 25
    • 24
    • 24
    • 23
    • 13
    • 13
    • 11
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human Annexin A1 protein
    Isotyp
    IgG2a
    Top Product
    Discover our top product ANXA1 Primärantikörper
  • Applikationshinweise

    Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: A549 or K562 cell lysates. Human esophagus, placenta or prostate.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
    Andere Bezeichnung
    ANXA1 (ANXA1 Produkte)
    Hintergrund
    ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35,Annexin A1 / (Hairy Cell Leukemia Marker)
    Cellular localisation: Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium, also found in the
    Molekulargewicht
    38kDa
    Gen-ID
    301, 494173
    UniProt
    P04083
    Pathways
    Hormone Transport
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