Rekombinanter FOXP1 Antikörper (AA 350-450)

Produktnummer ABIN7126476

Der Maus Monoklonal Anti-FOXP1-Antikörper wurde für IHC (f) validiert. Er ist geeignet, FOXP1 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter FOXP1 Antikörper (AA 350-450) (ABIN7126476)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Produktdetails anti-FOXP1 Antikörper

Bindungsspezifität: AA 350-450

Spezifität: Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( 80 % ) for FOXP1 is needed to achieve high specificity for the ABC subtype.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa350-450) of human FOXP1 protein (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human tonsil or colon.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Andere Bezeichnung: FOXP1

Hintergrund: Fork head related protein like B, Forkhead box protein P1 (FOXP1), Glutamine rich factor 1, hFKH1B, HSPC215, QRF1,FOXP1 (Transcription Factor)
Cellular localisation: Nucleus.

Molekulargewicht: 75kDa

Gen-ID: 27086

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response