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GDF9 Antikörper (C-Term)

Der Maus Monoklonal Anti-GDF9-Antikörper wurde für WB, ELISA, Coat und IHC (f) validiert. Er ist geeignet, GDF9 in Proben von Human zu detektieren.
Produktnummer ABIN7126467

Kurzübersicht für GDF9 Antikörper (C-Term) (ABIN7126467)

Target

Alle GDF9 Antikörper anzeigen
GDF9 (Growth Differentiation Factor 9 (GDF9))

Reaktivität

  • 60
  • 24
  • 22
  • 1
  • 1
Human

Wirt

  • 62
  • 6
  • 1
  • 1
  • 1
Maus

Klonalität

  • 66
  • 5
Monoklonal

Konjugat

  • 36
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GDF9 Antikörper ist unkonjugiert

Applikation

  • 59
  • 32
  • 28
  • 14
  • 13
  • 12
  • 10
  • 7
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Bindungsspezifität

    • 16
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    C-Term

    Spezifität

    GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9/4261 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Tuberculin coupled peptide with sequence VPAKYSPLSVLTIEPDGSIAYKEYEDMIATKC that recognizes an epitope with the EPDG sequence near the C-terminal region of human GDF9.

    Isotyp

    IgG1
  • Applikationshinweise

    Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human ovary.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    GDF9 (Growth Differentiation Factor 9 (GDF9))

    Andere Bezeichnung

    GDF9

    Hintergrund

    Growth/differentiation factor 9, GDF-9, GDF9,GDF9 (Growth Differentiation Factor 9)
    Cellular localisation: Cytoplasmic (secreted)

    Molekulargewicht

    51kDa

    Gen-ID

    2661, 25022

    UniProt

    O60383
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