ZHX3 Antikörper

Produktnummer ABIN7126397

Produktdetails anti-ZHX3 Antikörper

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZHX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS)

Spezifität: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ZHX3 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells),Optimal dilution for a specific application should be determined.

Positive_Control: Human kidney, brain or thyroid.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ZHX3

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Andere Bezeichnung: ZHX3 (ZHX3 Produkte)

Synonyme: tix1 antikoerper, zgc:110489 antikoerper, TIX1 antikoerper, 1810059C13Rik antikoerper, 4932418O04Rik antikoerper, 9530010N21Rik antikoerper, Tix1 antikoerper, mKIAA0395 antikoerper, zinc fingers and homeoboxes 3 antikoerper, zhx3 antikoerper, ZHX3 antikoerper, Zhx3 antikoerper

Hintergrund: KIAA0395, TIX1, Triple homeobox protein 1, ZHX 3, Zhx3, Zinc finger and homeodomain protein 3, Zinc fingers and homeoboxes protein 3,ZHX3 (Transcriptional Repressor)
Cellular localisation: Nucleus.

Molekulargewicht: 105kDa

Gen-ID: 23051, 380133

UniProt: Q9H4I2