TCF25 Antikörper

Produktnummer ABIN7126395

Produktdetails anti-TCF25 Antikörper

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCF25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

Kreuzreaktivität (Details): Human. Predicted to react with Mouse and Rat.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human TCF25 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu TCF25

Target: TCF25 (Transcription Factor 25 (Basic Helix-Loop-Helix) (TCF25))

Andere Bezeichnung: TCF25 (TCF25 Produkte)

Hintergrund: FKSG26, hKIAA1049, Hulp1, KIAA1049, Nuclear localized protein 1, NULP1, PRO2620, Transcription factor 25 (basic helix loop helix),TCF25
Cellular localisation: Nucleus. Some staining in the cytosol.

Molekulargewicht: 77kDa

Gen-ID: 22980, 415342

UniProt: Q9BQ70