CD5L Antikörper (AA 269-366)

Produktnummer ABIN7126363

Dieses Anti-CD5L-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD5L in IHC (f). Geeignet für Human.

Kurzübersicht für CD5L Antikörper (AA 269-366) (ABIN7126363)

Target: CD5L (CD5 Molecule-Like (CD5L))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD5L Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Produktdetails anti-CD5L Antikörper

Bindungsspezifität: AA 269-366

Spezifität: CD5L (CD5 Molecule-like), also known as API6, PRO229, Spi± or SP-ALPHA, is a 347 amino acid secreted protein that belongs to the scavenger receptor cysteine-rich (SRCR) family of leukocyte regulating proteins. Expressed in bone marrow, spleen, thymus, lymph node and fetal liver, CD5L is thought to be involved in regulating the immune system via binding to peripheral monocytes and mediating their activation and overall survival. CD5L has three cysteine-rich domains and, in addition to its role in the immune system, may function to inhibit apoptosis and promote macrophage survival.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: 293T, Ramos, or MOLT-4 cells. Human tonsil or lymph node.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Andere Bezeichnung: CD5L

Hintergrund: AAC-11, AIM, API6, APOPTOSIS INHIBITOR 6, APOPTOSIS INHIBITOR OF MACROPHAGES, CD5 antigen like (scavenger receptor cysteine rich family), CD5 antigen-like, CT-2, Highly similar to ANTIGEN WC1.1 [Bos taurus], IgM-associated peptide, Pdp, PRO229, SCAVENGER RECEPTOR CYSTEINE-RICH FAMILY, SP-alpha, Spalpha,CD5L / CD5LG / CD5 Ligand
Cellular localisation: Secreted.

Molekulargewicht: 38kDa

Gen-ID: 922, 134035

UniProt: O43866