DAXX Antikörper
-
- Target Alle DAXX Antikörper anzeigen
- DAXX (Death-Domain Associated Protein (DAXX))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser DAXX Antikörper ist unkonjugiert
-
Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human DAXX protein
- Isotyp
- IgG2b
- Top Product
- Discover our top product DAXX Primärantikörper
-
-
- Applikationshinweise
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
-
- Target
- DAXX (Death-Domain Associated Protein (DAXX))
- Andere Bezeichnung
- DAXX (DAXX Produkte)
- Synonyme
- BING2 antikoerper, DAP6 antikoerper, EAP1 antikoerper, LOC100226911 antikoerper, daxx antikoerper, si:dz179b20.7 antikoerper, wu:fd15c03 antikoerper, death domain associated protein antikoerper, Fas death domain-associated protein antikoerper, 28S ribosomal protein S29, mitochondrial antikoerper, death-domain associated protein antikoerper, death-associated protein 6 L homeolog antikoerper, DAXX antikoerper, Daxx antikoerper, LOC100226911 antikoerper, daxx.L antikoerper, daxx antikoerper
- Hintergrund
-
DAP6, EAP1, BING2, SMIM40,DAXX (Transcriptional Corepressor)
Cellular localisation: Nucleus. Cytoplasm. - Molekulargewicht
- 81.37kDa
- Gen-ID
- 1616, 336916
- UniProt
- Q9UER7
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
-