CTBP2 Antikörper
-
- Target Alle CTBP2 Antikörper anzeigen
- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CTBP2 Antikörper ist unkonjugiert
-
Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Spezifität
- The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human CTBP2 protein
- Isotyp
- IgG2b
- Top Product
- Discover our top product CTBP2 Primärantikörper
-
-
- Applikationshinweise
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Molt-4 or HeLa cells.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
-
- Target
- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
- Andere Bezeichnung
- CTBP2 (CTBP2 Produkte)
- Hintergrund
-
C-terminal-binding protein 2 (CTBP2), Ribeye,CTBP2 (C-terminal binding protein 2)
Cellular localisation: Nucleus. Cell junction > synapse. - Molekulargewicht
- 95.2kDa
- Gen-ID
- 1488, 501345
- UniProt
- P56545
-