CTBP2 Antikörper

Produktnummer ABIN7126266

Der Maus Monoklonal anti-CTBP2 Antikörper wird verwendet zum Nachweis von CTBP2 in Proben von Human. Er wurde validiert für IF und FACS.

Kurzübersicht für CTBP2 Antikörper (ABIN7126266)

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTBP2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-CTBP2 Antikörper

Spezifität: The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.

Kreuzreaktivität (Details): Human

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human CTBP2 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: Molt-4 or HeLa cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu CTBP2

Target: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Andere Bezeichnung: CTBP2

Hintergrund: C-terminal-binding protein 2 (CTBP2), Ribeye,CTBP2 (C-terminal binding protein 2)
Cellular localisation: Nucleus. Cell junction > synapse.

Molekulargewicht: 95.2kDa

Gen-ID: 1488, 501345

UniProt: P56545