Rekombinanter CNN1 Antikörper (C-Term)

Produktnummer ABIN7126242

Der Kaninchen Monoklonal anti-CNN1 Antikörper wird verwendet zum Nachweis von CNN1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter CNN1 Antikörper (C-Term) (ABIN7126242)

Target: CNN1 (Calponin 1 (CNN1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CNN1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: CNN1-4227R

Produktdetails anti-CNN1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Recombinant Calponin-1 (Smooth Muscle Marker) Antibody

Spezifität: Calponin a 33 kDa polypeptide, is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin. Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions. The antibody has been found in tissue extracts from smooth muscle, but not in fibroblast extracts.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified by Protein A/G.

Immunogen: Synthetic peptide corresponding to residues on the C-terminus of human Calponin was used as an immunogen

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: K562 cells. Myoepithelial cells in breast ducts or leiomyosarcoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CNN1

Target: CNN1 (Calponin 1 (CNN1))

Andere Bezeichnung: CNN1

Hintergrund:

Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin-1, CNN1, Cnn1, Sm Calp, SMCC

K562 cells. Myoepithelial cells in breast ducts or leiomyosarcoma.

Molekulargewicht: 33kDa

Gen-ID: 1264, 465929

UniProt: P51911