LRG1 Antikörper (AA 30-180)

Produktnummer ABIN7126226

Dieses Maus Monoklonal-Antikörper erkennt spezifisch LRG1 in IHC (f). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für LRG1 Antikörper (AA 30-180) (ABIN7126226)

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LRG1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Produktdetails anti-LRG1 Antikörper

Bindungsspezifität: AA 30-180

Spezifität: LRG1 (leucine-rich i±2-glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains 8 LRR (leucine-rich) repeats and one LRRCT domain. The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa 30-180) of human LRG1 protein (exact sequence is proprietary)

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human liver, pancreas or breast.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu LRG1

Target: LRG1 (Leucine-Rich alpha-2 Glycoprotein 1 (LRG1))

Andere Bezeichnung: LRG1

Hintergrund: 1300008B03Rik, 2310031E04Rik, A2GL, HMFT1766, Leucine-rich alpha-2-glycoprotein 1, Leucine-rich alpha-2-glycoprotein precursor, LRG1,LRG1 / Leucine Rich alpha-2-glycoprotein 1
Cellular localisation: Secreted.

Molekulargewicht: 38kDa

Gen-ID: 116844, 655559

UniProt: P02750

Pathways: Brown Fat Cell Differentiation