FTCD Antikörper
Kurzübersicht für FTCD Antikörper (ABIN7126207)
Target
Alle FTCD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- The antibody recognizes an epitope located on the microtubule-binding peripheral Golgi membrane 58 kDa protein. It is also useful for studies on the effect of microtubule-perturbing agents on the Golgi apparatus.The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively-spliced transcript variants have been found for this gene. Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi.
-
Kreuzreaktivität (Details)
- Human. Predicted to react in Mouse, Rat, Bovine, Dog, Hamster, Pig, Monkey and Kangaroo rat.
-
Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
-
Immunogen
- 58K Golgi Protein purified from rat liver.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or HepG2 cells. Human kidney or liver tissue.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
-
Konservierungsmittel
- Azide free
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
-
Haltbarkeit
- 24 months
-
-
- FTCD (Formiminotransferase Cyclodeaminase (FTCD))
-
Andere Bezeichnung
- FTCD
-
Hintergrund
-
Formimidoyltetrahydrofolate cyclodeaminase, Formiminotetrahydrofolate cyclodeaminase, Formiminotransferase cyclodeaminase, Glutamate formiminotransferase, Glutamate formyltransferase, LCHC1,FTCD / 58K Golgi Protein
Cellular localisation: Cytoplasm. Golgi apparatus. -
Molekulargewicht
- 59kDa
-
Gen-ID
- 10841, 415846
-
UniProt
- O95954
Target
-