Der Kaninchen Polyklonal Anti-ZWILCH-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, ZWILCH in Proben von Human, Maus und Ratte zu detektieren.
Synonyms:FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH Background:Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).