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WWP1 Antikörper

WWP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IP, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7120866
  • Target Alle WWP1 Antikörper anzeigen
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    Reaktivität
    • 23
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 19
    • 5
    Kaninchen
    Klonalität
    • 20
    • 4
    Polyklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WWP1 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    WW domain containing E3 ubiquitin protein ligase 1
    Isotyp
    IgG
    Top Product
    Discover our top product WWP1 Primärantikörper
  • Applikationshinweise
    WB: 1:200-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    Andere Bezeichnung
    WWP1 (WWP1 Produkte)
    Synonyme
    AIP5 antikoerper, Tiul1 antikoerper, hSDRP1 antikoerper, 8030445B08Rik antikoerper, SDRP1 antikoerper, WWP1 antikoerper, aip5 antikoerper, tiul1 antikoerper, hsdrp1 antikoerper, WW domain containing E3 ubiquitin protein ligase 1 antikoerper, WWP1 antikoerper, Wwp1 antikoerper, wwp1 antikoerper
    Hintergrund
    Synonyms:AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1 Background:E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
    Molekulargewicht
    95 kDa
    Gen-ID
    11059
    UniProt
    Q9H0M0
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