WT1 Antikörper
Kurzübersicht für WT1 Antikörper (ABIN7120843)
Target
Alle WT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- WT1 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- Wilms tumor 1
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IHC: 1:50-1:500, IF: 1:20-1:200, IP: 1:500-1:5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- WT1 (Wilms Tumor 1 (WT1))
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Andere Bezeichnung
- WT1
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Hintergrund
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Synonyms: Wilms tumor protein|WT33|WT1
Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
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Molekulargewicht
- 52 kDa
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Gen-ID
- 7490
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UniProt
- P19544
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Pathways
- Tube Formation
Target
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