WDR1 Antikörper

Produktnummer ABIN7120810

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WDR1 in WB, IHC, ELISA und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für WDR1 Antikörper (ABIN7120810)

Target: WDR1 (WD Repeat Domain 1 (WDR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-WDR1 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: WD repeat domain 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu WDR1

Target: WDR1 (WD Repeat Domain 1 (WDR1))

Andere Bezeichnung: WDR1

Hintergrund: Synonyms:Actin interacting protein 1, AIP1, NORI 1, WD repeat containing protein 1, WD repeat domain 1, WDR1 Background:Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins(PubMed:15629458). Enhances cofilin-mediated actin severing(By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions(PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance(By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity(PCP) during follicular epithelium development and for cell shape changes during PCP, the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension(By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt(PubMed:25792565).

Molekulargewicht: 66 kDa

Gen-ID: 9948

UniProt: O75083

Pathways: Sensory Perception of Sound