Dieses Anti-WRAP53-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von WRAP53 in WB, IHC, ELISA und IP. Geeignet für Human, Maus und Ratte.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
WRAP53
(WD Repeat Containing, Antisense To TP53 (WRAP53))
Andere Bezeichnung
WRAP53
Hintergrund
Synonyms:FLJ10385, TCAB1, WDR79, WRAP53 Background:Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.