VAMP8 Antikörper (AA 1-75)

Produktnummer ABIN7120762

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VAMP8 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für VAMP8 Antikörper (AA 1-75) (ABIN7120762)

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAMP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-VAMP8 Antikörper

Bindungsspezifität: AA 1-75

Verwendungszweck: VAMP8 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-75aa

Immunogen: vesicle-associated membrane protein 8(endobrevin)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu VAMP8

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Andere Bezeichnung: VAMP8

Hintergrund:

Synonyms: Vesicle-associated membrane protein 8 (VAMP-8)|Endobrevin (EDB)|VAMP8

Background: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).

Molekulargewicht: 15 kDa

Gen-ID: 8673

UniProt: Q9BV40