VEGF Antikörper

Produktnummer ABIN7120740

Dieses Anti-VEGF-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von VEGF in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für VEGF Antikörper (ABIN7120740)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VEGF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 5H5

Produktdetails anti-VEGF Antikörper

Aufreinigung: protein A+G purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: vascular endothelial growth factor A

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:4000, IHC: 1:50-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01MPBS pH 7.4,

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Andere Bezeichnung: VEGF

Hintergrund: Synonyms:L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF Background:VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010). This antibody can recognize all the isoforms of VEFGA.

Molekulargewicht: 45 kDa

UniProt: P15692