Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VAPA in WB, IHC, ELISA, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
VAPA
(VAMP (Vesicle-Associated Membrane Protein)-Associated Protein A, 33kDa (VAPA))
Andere Bezeichnung
VAPA
Hintergrund
Synonyms:33 kDa VAMP associated protein, hVAP 33, VAMP A, VAMP associated protein A, VAP 33, VAP A, VAP33, VAPA Background:Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).