VPS8 Antikörper
Kurzübersicht für VPS8 Antikörper (ABIN7120719)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- vacuolar protein sorting 8 homolog(S. cerevisiae)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000,IP: 1:200-1:2000, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- VPS8 (Vacuolar Protein Sorting 8 Homolog (VPS8))
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Andere Bezeichnung
- VPS8
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Hintergrund
- Synonyms:FLJ32099, KIAA0804, VPS8 Background:Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).
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Molekulargewicht
- 151 kDa
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Gen-ID
- 23355
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UniProt
- Q8N3P4
Target
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