Uromodulin Antikörper
Kurzübersicht für Uromodulin Antikörper (ABIN7120648)
Target
Alle Uromodulin (UMOD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- uromodulin
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:200-1:2000, IHC: 1:20-1:500, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- Uromodulin (UMOD)
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Andere Bezeichnung
- Uromodulin
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Hintergrund
- Synonyms:ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, UMOD, uromodulin Background:Uromodulin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases.(PMID: 21654721)
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Molekulargewicht
- 55-70 kDa
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UniProt
- P07911
Target
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