UBE2K Antikörper

Produktnummer ABIN7120554

Produktdetails anti-UBE2K Antikörper

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2K Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin-conjugating enzyme E2K

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Andere Bezeichnung: UBE2K (UBE2K Produkte)

Synonyme: E2-25K antikoerper, HIP2 antikoerper, HYPG antikoerper, LIG antikoerper, UBC1 antikoerper, E2-25k antikoerper, Hip2 antikoerper, Hypg antikoerper, Lig antikoerper, e2-25k antikoerper, hip2 antikoerper, hypg antikoerper, lig antikoerper, AW492011 antikoerper, D5Ertd601e antikoerper, ube2k antikoerper, zgc:103472 antikoerper, zgc:110791 antikoerper, ubiquitin conjugating enzyme E2 K antikoerper, ubiquitin-conjugating enzyme E2K antikoerper, ubiquitin conjugating enzyme E2 K S homeolog antikoerper, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) antikoerper, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) antikoerper, UBE2K antikoerper, Ube2k antikoerper, ube2k.S antikoerper, ube2k antikoerper, ube2kb antikoerper, ube2ka antikoerper

Hintergrund: Synonyms:DKFZp564C1216, DKFZp686J24237, E2-25K, HIP 2, HIP2, HYPG, LIG, UBE2K, Ubiquitin carrier protein, Ubiquitin protein ligase Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation(ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.

Molekulargewicht: 25 kDa

Gen-ID: 3093

UniProt: P61086