USP37 Antikörper

Produktnummer ABIN7120518

Produktdetails anti-USP37 Antikörper

Target: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 37

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu USP37

Target: USP37 (Ubiquitin Specific Peptidase 37 (USP37))

Andere Bezeichnung: USP37 (USP37 Produkte)

Synonyme: 4932415L06Rik antikoerper, C330008N13Rik antikoerper, wu:fi15b04 antikoerper, wu:fi38d03 antikoerper, zgc:152882 antikoerper, zgc:153999 antikoerper, ubiquitin specific peptidase 37 antikoerper, USP37 antikoerper, usp37 antikoerper, Usp37 antikoerper

Hintergrund: Synonyms:Deubiquitinating enzyme 37, KIAA1594, Ubiquitin thiolesterase 37, USP37 Background:Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).

Molekulargewicht: 110 kDa,70 kDa

Gen-ID: 57695

UniProt: Q86T82