USP37 Antikörper
Kurzübersicht für USP37 Antikörper (ABIN7120518)
Target
Alle USP37 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ubiquitin specific peptidase 37
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
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Andere Bezeichnung
- USP37
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Hintergrund
- Synonyms:Deubiquitinating enzyme 37, KIAA1594, Ubiquitin thiolesterase 37, USP37 Background:Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
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Molekulargewicht
- 110 kDa,70 kDa
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Gen-ID
- 57695
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UniProt
- Q86T82
Target
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