USP34 Antikörper
Kurzübersicht für USP34 Antikörper (ABIN7120515)
Target
Alle USP34 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- USP34 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ubiquitin specific peptidase 34
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- USP34 (Ubiquitin Specific Peptidase 34 (USP34))
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Andere Bezeichnung
- USP34
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Hintergrund
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 34|Deubiquitinating enzyme 34|Ubiquitin thioesterase 34|Ubiquitin-specific-processing protease 34|USP34|KIAA0570|KIAA0729
Background: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
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Molekulargewicht
- 47 kDa
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Gen-ID
- 9736
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UniProt
- Q70CQ2
Target
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