USP1 Antikörper (AA 430-785)
Kurzübersicht für USP1 Antikörper (AA 430-785) (ABIN7120490)
Target
Alle USP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 430-785
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Verwendungszweck
- USP1 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 430-785aa
Immunogen: ubiquitin specific peptidase 1
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:1000-1:10000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- USP1 (Ubiquitin Specific Peptidase 1 (USP1))
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Andere Bezeichnung
- USP1
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Hintergrund
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 1|Deubiquitinating enzyme 1 (hUBP)|Ubiquitin thioesterase 1|Ubiquitin-specific-processing protease 1|Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment|USP1
Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
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Molekulargewicht
- 90 kDa
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Gen-ID
- 7398
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UniProt
- O94782
Target
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