TBCD Antikörper
Kurzübersicht für TBCD Antikörper (ABIN7120359)
Target
Alle TBCD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- TBCD antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- tubulin folding cofactor D
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- TBCD (Tubulin Folding Cofactor D (TBCD))
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Andere Bezeichnung
- TBCD
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Hintergrund
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Synonyms: Tubulin-specific chaperone D|Beta-tubulin cofactor D (tfcD)|SSD-1|Tubulin-folding cofactor D|TBCD|KIAA0988|SSD1|TFCD
Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
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Molekulargewicht
- 130 kDa
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Gen-ID
- 6904
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UniProt
- Q9BTW9
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Pathways
- Cell-Cell Junction Organization
Target
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