TRIM37 Antikörper
Kurzübersicht für TRIM37 Antikörper (ABIN7120286)
Target
Alle TRIM37 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- TRIM37 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- tripartite motif-containing 37
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- TRIM37 (Tripartite Motif Containing 37 (TRIM37))
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Andere Bezeichnung
- TRIM37
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Hintergrund
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Synonyms: E3 ubiquitin-protein ligase TRIM37|Mulibrey nanism protein|RING-type E3 ubiquitin transferase TRIM37|Tripartite motif-containing protein 37|TRIM37|KIAA0898|MUL|POB1
Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication(PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication(PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A(H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group(PcG) multiprotein PRC2-like complex and mediates repression of target genes(PubMed:25470042). Has anti-HIV activity(PubMed:24317724).
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Molekulargewicht
- 100 kDa, 130 kDa
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Gen-ID
- 4591
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UniProt
- O94972
Target
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