TRIB3 Antikörper
Kurzübersicht für TRIB3 Antikörper (ABIN7120255)
Target
Alle TRIB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- tribbles homolog 3(Drosophila)
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Isotyp
- IgG
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anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibody
TRIB3 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 3D7 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibodyTRIB3 Reaktivität: Human WB, ELISA, IF, RNAi Wirt: Maus Monoclonal 1H2 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 15-45), (N-Term) antibodyTRIB3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4069-RB4070 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 152-325) antibodyTRIB3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (C-Term) antibodyTRIB3 Reaktivität: Human IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 201-300) antibodyTRIB3 Reaktivität: Human, Ratte ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 301-331), (C-Term) antibodyTRIB3 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB4072 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (Internal Region) antibodyTRIB3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 1-358) antibodyTRIB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 1-358) antibodyTRIB3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:5000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
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Andere Bezeichnung
- TRIB3
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Hintergrund
- Synonyms:C20orf97, NIPK, SINK, SKIP3, TRB 3, TRB3, TRIB3, Tribbles homolog 3 Background:Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress. Can inhibit APOBEC3A editing of nuclear DNA.
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Molekulargewicht
- 42 kDa
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Gen-ID
- 57761
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UniProt
- Q96RU7
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha
Target
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