Dieses Anti-TFE3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TFE3 in WB, ELISA, IHC und IP. Geeignet für Human, Maus und Ratte.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
TFE3
(Transcription Factor E3 (TFE3))
Andere Bezeichnung
TFE3
Hintergrund
Synonyms:bHLHe33, RCCP2, TFE3, TFEA, Transcription factor E3 Background:Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.