TFE3 Antikörper (AA 1-300)
Kurzübersicht für TFE3 Antikörper (AA 1-300) (ABIN7120074)
Target
Alle TFE3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-300
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Verwendungszweck
- TFE3 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-300aa
Immunogen: transcription factor binding to IGHM enhancer 3
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- TFE3 (Transcription Factor E3 (TFE3))
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Andere Bezeichnung
- TFE3
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Hintergrund
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Synonyms: Transcription factor E3|Class E basic helix-loop-helix protein 33 (bHLHe33)|TFE3|BHLHE33
Background: Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
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Molekulargewicht
- 65 kDa
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Gen-ID
- 7030
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UniProt
- P19532
Target
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