TRIP4 Antikörper

Produktnummer ABIN7119957

Dieser Anti-TRIP4-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von TRIP4 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TRIP4 Antikörper (ABIN7119957)

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRIP4 Antikörper

Verwendungszweck: TRIP4 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: thyroid hormone receptor interactor 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TRIP4

Target: TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))

Andere Bezeichnung: TRIP4

Hintergrund:

Synonyms: Activating signal cointegrator 1 (ASC-1)|Thyroid receptor-interacting protein 4 (TR-interacting protein 4, TRIP-4)|TRIP4|RQT4

Background: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation(PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation(By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B(PubMed:12077347). May play a role in the development of neuromuscular junction(PubMed:26924529).

Molekulargewicht: 66 kDa

Gen-ID: 9325

UniProt: Q15650