THOC7 Antikörper

Produktnummer ABIN7119929

Der Kaninchen Polyklonal Anti-THOC7-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, THOC7 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für THOC7 Antikörper (ABIN7119929)

Target: THOC7 (THO Complex 7 (THOC7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THOC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-THOC7 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: THO complex 7 homolog(Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu THOC7

Target: THOC7 (THO Complex 7 (THOC7))

Andere Bezeichnung: THOC7

Hintergrund: Synonyms:NIF3L1BP1 Background:Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production.

Molekulargewicht: 24 kDa

Gen-ID: 80145

UniProt: Q6I9Y2