TELO2 Antikörper

Produktnummer ABIN7119825

Dieses Anti-TELO2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TELO2 in WB, ELISA, IHC, IF und IP. Geeignet für Human.

Kurzübersicht für TELO2 Antikörper (ABIN7119825)

Target: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TELO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 8B6

Produktdetails anti-TELO2 Antikörper

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: TEL2, telomere maintenance 2, homolog(S. cerevisiae)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:4000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu TELO2

Target: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Andere Bezeichnung: TELO2

Hintergrund: Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.

Molekulargewicht: 92 kDa

Gen-ID: 9894

UniProt: Q9Y4R8