TBC1D17 Antikörper (AA 1-350)
Kurzübersicht für TBC1D17 Antikörper (AA 1-350) (ABIN7119799)
Target
Alle TBC1D17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-350
-
Verwendungszweck
- TBC1D17 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
-
Immunogen sequence: 1-350aa
Immunogen: TBC1 domain family, member 17
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
-
Andere Bezeichnung
- TBC1D17
-
Hintergrund
-
Synonyms: TBC1 domain family member 17|TBC1D17
Background: Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
-
Molekulargewicht
- 73-100 kDa
-
Gen-ID
- 79735
-
UniProt
- Q9HA65
Target
-