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SNCA Antikörper
SNCA
Reaktivität: Human, Ratte, Maus
WB, ELISA, IHC
Wirt: Maus
Monoclonal
5C6
unconjugated
Produktnummer ABIN7119723
Produktdetails anti-SNCA Antikörper
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Target
Alle SNCA Antikörper anzeigen
SNCA
(Synuclein, alpha (SNCA))
Reaktivität
Alle Reaktivitäten für SNCA Antikörper
Human, Ratte, Maus
Wirt
Alle Wirte für SNCA Antikörper
Maus
Klonalität
Alle Klonalitäten für SNCA Antikörper
Monoklonal
Konjugat
Alle Konjugate für SNCA Antikörper
Dieser SNCA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SNCA Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Aufreinigung
protein A+G purified
Reinheit
≥95 % as determined by SDS-PAGE
Immunogen
synuclein, alpha (non A4 component of amyloid precursor)
Klon
5C6
Isotyp
IgG1
Top Product
Discover our top product SNCA Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1:500 - 1:2000, IHC: 1:500 - 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Details zu SNCA
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Target
SNCA
(Synuclein, alpha (SNCA))
Andere Bezeichnung
alpha-synuclein (SNCA Produkte )
Synonyme
snca antikoerper, MGC64356 antikoerper, LOC619283 antikoerper, NACP antikoerper, alphaSYN antikoerper, PARK1 antikoerper, PARK4 antikoerper, PD1 antikoerper, synuclein alpha L homeolog antikoerper, alpha-synuclein antikoerper, synuclein alpha antikoerper, synuclein, alpha antikoerper, snca.L antikoerper, LOC619283 antikoerper, SNCA antikoerper, Snca antikoerper
Hintergrund
Synonyms:Alpha synuclein, NACP, PARK1, PARK4, SNCA Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Molekulargewicht
18 kDa
Gen-ID
6622
UniProt
P37840
Pathways
Synaptic Membrane , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Platelet-derived growth Factor Receptor Signaling , Negative Regulation of Transporter Activity , Regulation of long-term Neuronal Synaptic Plasticity
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