STEAP3 Antikörper

Produktnummer ABIN7119514

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STEAP3 in WB, ELISA, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für STEAP3 Antikörper (ABIN7119514)

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-STEAP3 Antikörper

Verwendungszweck: STEAP3 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: STEAP family member 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Andere Bezeichnung: STEAP3

Hintergrund:

Synonyms: Metalloreductase STEAP3|Dudulin-2|Six-transmembrane epithelial antigen of prostate 3|Tumor suppressor-activated pathway protein 6 (hTSAP6)| pH yde (h pH yde)|STEAP3|TSAP6

Background: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Molekulargewicht: 55 kDa

Gen-ID: 55240

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis