Sorbs2 Antikörper

Produktnummer ABIN7119344

Der Kaninchen Polyklonal Anti-Sorbs2-Antikörper wurde für ELISA und IP validiert. Er ist geeignet, Sorbs2 in Proben von Human und Maus zu detektieren.

Kurzübersicht für Sorbs2 Antikörper (ABIN7119344)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sorbs2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunoprecipitation (IP)

Produktdetails anti-Sorbs2 Antikörper

Verwendungszweck: SORBS2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: sorbin and SH3 domain containing 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Andere Bezeichnung: SORBS2

Hintergrund:

Synonyms: Sorbin and SH3 domain-containing protein 2|Arg-binding protein 2 (ArgBP2)|Arg/Abl-interacting protein 2|Sorbin|SORBS2|ARGBP2|KIAA0777

Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Gen-ID: 8470

UniProt: O94875