Dieses Anti-SLC39A8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SLC39A8 in WB, ELISA, IHC, IF und IP. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7119306
Kurzübersicht für SLC39A8 Antikörper (ABIN7119306)
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
SLC39A8
(Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
Andere Bezeichnung
ZIP8
Hintergrund
Synonyms:BIGM103, PP3105, SLC39A8, ZIP 8, ZIP8 Background:SLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.