STK36 Antikörper

Produktnummer ABIN7118925

Produktdetails anti-STK36 Antikörper

Target: STK36 (serine/threonine Kinase 36 (STK36))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK36 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: serine/threonine kinase 36, fused homolog(Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu STK36

Target: STK36 (serine/threonine Kinase 36 (STK36))

Andere Bezeichnung: STK36 (STK36 Produkte)

Synonyme: FU antikoerper, fused-like antikoerper, 1700112N14Rik antikoerper, B930045J24 antikoerper, Fused antikoerper, mKIAA1278 antikoerper, fu antikoerper, si:dkey-180i4.3 antikoerper, zgc:152944 antikoerper, serine/threonine kinase 36 antikoerper, serine/threonine kinase 36 (fused homolog, Drosophila) antikoerper, STK36 antikoerper, Stk36 antikoerper, stk36 antikoerper

Hintergrund: Synonyms:KIAA1278 Background:Serine/threonine protein kinase which plays an important role in the sonic hedgehog(Shh) pathway by regulating the activity of GLI transcription factors(PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization(PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur(PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function(By similarity). Essential for construction of the central pair apparatus of motile cilia.

Molekulargewicht: 144 kDa

Gen-ID: 27148

UniProt: Q9NRP7