SRRM1 Antikörper

Produktnummer ABIN7118908

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SRRM1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Maus, Human und Ratte.

Kurzübersicht für SRRM1 Antikörper (ABIN7118908)

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SRRM1 Antikörper

Verwendungszweck: SRRM1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: serine/arginine repetitive matrix 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu SRRM1

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Andere Bezeichnung: SRRM1

Hintergrund:

Synonyms: Serine/arginine repetitive matrix protein 1|SR-related nuclear matrix protein of 160 kDa (SRm160)|Ser/Arg-related nuclear matrix protein|SRRM1|SRM160

Background: Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer(ESE)-dependent splicing activation by bridging together sequence-specific(SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP(SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.

Molekulargewicht: 120-160 kDa

Gen-ID: 10250

UniProt: Q8IYB3