SAFB Antikörper
Kurzübersicht für SAFB Antikörper (ABIN7118797)
Target
Alle SAFB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- SAFB antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- scaffold attachment factor B
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- SAFB (Scaffold Attachment Factor B (SAFB))
-
Andere Bezeichnung
- SAFB
-
Hintergrund
-
Synonyms: Scaffold attachment factor B1 (SAF-B, SAF-B1)|HSP27 estrogen response element-TATA box-binding protein (HSP27 ERE-TATA-binding protein)|SAFB|HAP|HET|SAFB1
Background: Binds to scaffold/matrix attachment region(S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex(consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing(By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter(By similarity). Can inhibit cell proliferation.
-
Molekulargewicht
- 150 kDa
-
Gen-ID
- 6294
-
UniProt
- Q15424
-
Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
-