RBM25 Antikörper

Produktnummer ABIN7118681

Produktdetails anti-RBM25 Antikörper

Target: RBM25 (RNA Binding Motif Protein 25 (RBM25))

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding motif protein 25

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu RBM25

Target: RBM25 (RNA Binding Motif Protein 25 (RBM25))

Andere Bezeichnung: RBM25 (RBM25 Produkte)

Synonyme: fi03e10 antikoerper, zgc:56208 antikoerper, wu:fi03e10 antikoerper, si:ch211-105d18.5 antikoerper, rnpc7 antikoerper, s164 antikoerper, NET52 antikoerper, RED120 antikoerper, RNPC7 antikoerper, S164 antikoerper, Snu71 antikoerper, fSAP94 antikoerper, 2600011C06Rik antikoerper, 2610015J01Rik antikoerper, A130095G20Rik antikoerper, AI159652 antikoerper, AL023075 antikoerper, AU043498 antikoerper, RNA binding motif protein 25b antikoerper, RNA binding motif protein 25 antikoerper, RNA binding motif protein 25 S homeolog antikoerper, putative rna binding motif protein 25 antikoerper, rbm25b antikoerper, Rbm25 antikoerper, rbm25.S antikoerper, rbm25 antikoerper, RBM25 antikoerper, Smp_078610 antikoerper

Hintergrund: Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.

Molekulargewicht: 110-120 kDa

Gen-ID: 58517

UniProt: P49756