RNF6 Antikörper
Kurzübersicht für RNF6 Antikörper (ABIN7118660)
Target
Alle RNF6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ring finger protein(C3H2C3 type) 6
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- RNF6 (RING Finger Protein 6 (RNF6))
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Andere Bezeichnung
- RNF6
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Hintergrund
- Synonyms:SPG2 Background:E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
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Molekulargewicht
- 78 kDa
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Gen-ID
- 6049
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UniProt
- Q9Y252
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
Target
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